Variable Shape Attitude Control Demonstration with Microsat Hibari

This paper presents the ongoing feasibility study and bus system for microsatellite “Hibari”. The main technical missions for Hibari is called “Variable Shape Attitude Control (VSAC)”. This VSAC is based on an idea to utilize a reaction torque when a part of the satellite structure, for example, solar array paddles is appropriately rotated by actuators. The previous research concluded that VSAC successfully achieved the rapid maneuvering while maintain the high attitude stability against disturbances [1], and thus, it can be applied to a variety of advanced attitude control missions. Hibari project also aims at its application to astronomical mission requiring high pointing stability and agile maneuvering. This paper is mainly comprised of 3 parts: detail mission statement, ongoing feasibility studies and bus system configuration. First, we mention the mission requirement and detail mission sequence for both technical and science missions. Second, we show the ongoing feasibility studies to confirm that all mission requirement is satisfied by VSAC. Third, this paper describes each subsystem configuration to meet the system requirement stated in the mission’s section. And then, we wrap up in the conclusion section and stated the future study for advanced VSAC use in the end

Development of Attitude Sensor using Deep Learning

A new method for attitude determination utilizing color earth images taken with COTS visible light camera is presented. The traditional earth camera has been used for coarse attitude determination by detecting the edge of the earth, and therefore it can only provide coarse and 2-axis information. In contrast, our method recognizes the ground pattern with an accuracy of sub-degrees and can provide 3-axis attitude information by comparing the detected ground pattern and the global map. Moreover, this method has advantages in the size, mass and cost of the detector system which consists of a cheap optical color camera and a single board computer. To demonstrate the method in space, we have developed a sensor system named “Deep Learning Attitude Sensor (DLAS)”. DLAS uses COTS camera modules and single board computers to reduce the cost. The obtained images are promptly analyzed with a newly developed real-time image recognition algorithms

Increased serum HO-1 in hemophagocytic syndrome and adult-onset Still's disease: use in the differential diagnosis of hyperferritinemia

Heme oxygenase-1 (HO-1), an inducible heme-degrading enzyme, is expressed by macrophages and endothelial cells in response to various stresses. Because ferritin synthesis is stimulated by Fe(2+), which is a product of heme degradation, we examined the relation between HO-1 and ferritin levels in the serum of patients with hemophagocytic syndrome (HPS), adult-onset Still's disease (ASD), and other diseases that may cause hyperferritinemia. Seven patients with HPS, 10 with ASD, 73 with other rheumatic diseases, 20 with liver diseases, 10 recipients of repeated blood transfusion because of hematological disorders, and 22 healthy volunteers were enrolled. Serum HO-1 and ferritin levels were determined by ELISA. Expression of HO-1 mRNA and protein by peripheral blood mononuclear cells (PBMCs) was determined by real-time PCR and immunocytochemical techniques, respectively. Serum levels of HO-1 were significantly higher in patients with active HPS and ASD than in the other groups (P < 0.01). HO-1 levels were not elevated in patients with other causes of hyperferritinemia but were moderately elevated in patients with dermatomyositis/polymyositis. Among patients with HPS and ASD, serum HO-1 levels correlated closely with serum ferritin levels, and the levels of both returned to normal after therapy had induced remission. Increased expression of HO-1 mRNA was confirmed in PBMCs from some patients with HPS and ASD. Hyperferritinemia correlated closely with increased serum HO-1 in patients with HPS and ASD but not other conditions, indicating that measurement of serum HO-1 and ferritin levels would be useful in the differential diagnosis of hyperferritinemia and perhaps also in monitoring disease activity in HPS and ASD

HASC2011corpus: Towards the Common Ground of Human Activity Recognition

UbiComp '11 Proceedings of the 13th international conference on Ubiquitous computing, September 17-21, 2011, Beijing, ChinaHuman activity recognition through the wearable sensor will enable a next-generation human-oriented biquitous computing. However, most of research on human activity recognition so far is based on small number of subjects, and non-public data. To overcome the situation, we have gathered 4897 accelerometer data with 116 subjects and compose them as HASC2011corpus. In the field of pattern recognition, it is very important to evaluate and to improve the recognition methods by using the same dataset as a common ground. We make the HASC2011corpus into public for the research community to use it as a common ground of the Human Activity Recognition. We also show several facts and results of obtained from the corpus

Endoscopic submucosal dissection of a minute intramucosal adenocarcinoma in Barrett\u27s esophagus.

A 73-year-old man with short segmental Barrett\u27s esophagus underwent esophagoscopy, and a slightly depressed, discolored lesion was found on the anterior wall of the lower esophagus. Under a provisional diagnosis of differentiated adenocarcinoma without local lymph node metastasis, endoscopic submucosal dissection (ESD) was carried out. En bloc resection with tumor-free lateral/basal margins was accomplished without complication. The resected area was 12 x 15 mm in size, whereas the neoplastic lesion was 4 x 4 mm. Histopathological examination confirmed intramucosal well-differentiated tubular adenocarcinoma without angiolymphatic invasion adjacent to the muscularis mucosae. Repeated esophagoscopy 6 months after ESD showed neither locally recurrent nor metachronous lesions. Considering that Barrett\u27s esophagus is a precancerous condition, one may recommend eradication of both the neoplastic and non-neoplastic lesion with using ESD.Without Figure

Development and Initial On-orbit Performance of Multi-Functional Attitude Sensor using Image Recognition

This paper describes a multi-functional attitude sensor mounted on the “Innovative Satellite 1st” led by Japan Aerospace Exploration Agency which was launched in January 2019. In order to achieve the high accuracy determination in low cost, we developed a novel attitude sensor utilizing real-time image recognition technology, named “Deep Learning Attitude Sensor (DLAS)”. DLAS has two type of attitude sensors: Star Tracker(STT) and Earth Camera (ECAM). For the low-cost development, we adopted commercial off-the-shelf cameras. DLAS uses real-time image recognition technology and a new attitude determination algorithm. In this paper, we present the missions, methods and system configuration of DLAS and initial results of on-orbit experiment that was conducted after the middle of February 2019, and it is confirmed that attitude determinations using ECAM and STT are performed correctly

Endoscopic Polypectomy of Esophageal Leiomyomas; Report of Two Cases

We describe esophageal leiomyomas in two young patients (aged 35 and 32 years), who complained of dysphagia and epigastralgia, which were successfully treated by endoscopic polypectomy. Upper endoscopy showed a pedunculated polyp beneath the normal mucosa located at 28 cm from the incisor in the first case and 1 cm sessile 2.1 cm semipedunculated polypoid lesion in the lower esophagus just above the esophageal-gastric junction in the second case. Both lesions were resected by snare polypectomy without any complication. Light microscopic examination and immunohistochemistry of the tumor tissue confirmed the diagnosis of leiomyoma. Endoscopic polypectomy of esophageal leiomyoma is safe and should be considered as an optional treatment modality whenever possible

Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion

タンパク質の抗体ラベリング技術を改良し、構造解析をアシスト --電子顕微鏡やX線結晶解析による構造決定を加速化--. 京都大学プレスリリース. 2021-04-20.Antibody labeling has been conducted extensively for structure determination using both X-ray crystallography and electron microscopy (EM). However, establishing target-specific antibodies is a prerequisite for applying antibody-assisted structural analysis. To expand the applicability of this strategy, an alternative method has been developed to prepare an antibody complex by inserting an exogenous epitope into the target. It has already been demonstrated that the Fab of the NZ-1 monoclonal antibody can form a stable complex with a target containing a PA12 tag as an inserted epitope. Nevertheless, it was also found that complex formation through the inserted PA12 tag inevitably caused structural changes around the insertion site on the target. Here, an attempt was made to improve the tag-insertion method, and it was consequently discovered that an alternate tag (PA14) could replace various loops on the target without inducing large structural changes. Crystallographic analysis demonstrated that the inserted PA14 tag adopts a loop-like conformation with closed ends in the antigen-binding pocket of the NZ-1 Fab. Due to proximity of the termini in the bound conformation, the more optimal PA14 tag had only a minor impact on the target structure. In fact, the PA14 tag could also be inserted into a sterically hindered loop for labeling. Molecular-dynamics simulations also showed a rigid structure for the target regardless of PA14 insertion and complex formation with the NZ-1 Fab. Using this improved labeling technique, negative-stain EM was performed on a bacterial site-2 protease, which enabled an approximation of the domain arrangement based on the docking mode of the NZ-1 Fab

HASC2011corpus: Towards the Common Ground of Human Activity Recognition

Human activity recognition through the wearable sensor will enable a next-generation human-oriented biquitous computing. However, most of research on human activity recognition so far is based on small number of subjects, and non-public data. To overcome the situation, we have gathered 4897 accelerometer data with 116 subjects and compose them as HASC2011corpus. In the field of pattern recognition, it is very important to evaluate and to improve the recognition methods by using the same dataset as a common ground. We make the HASC2011corpus into public for the research community to use it as a common ground of the Human Activity Recognition. We also show several facts and results of obtained from the corpus.UbiComp \u2711 Proceedings of the 13th international conference on Ubiquitous computing, September 17-21, 2011, Beijing, Chin